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According to meta-analysis data, hypothyroidism occurs in about 3.8% of patients treated with anti-CTLA-4, 3.9% with anti-PD-L1, 7.0% with anti-PD-1, and 13.2% with combination therapy

In order to make supplements, bacterial cultures are allowed to ferment to produce the vitamin B12

10.1097/01.brs.0000209335.57767.b5 66 SainohT.OritaS.MiyagiM.InoueG.KamodaH.IshikawaT.et al (2016)

[36] Dressler, C., Blumeyer, A., Rosumeck, S., Arayesh, A., & Nast, A

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