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Nat Struct Mol Biol

Levtchenko E, Servais A, Hulton SA, Ariceta G, Emma F, Game DS, Lange K, Lapatto R, Liang H, Sberro-Soussan R, Topaloglu R, Das AM, Webb NJA, Wanner C (2022) Expert guidance on the multidisciplinary management of cystinosis in adolescent and adult patients

E., Huang & Sinicrope, F

Low levels of GSH lead to inflammation, a hallmark of CF, and oxidative stress that can lead to damage to cell membranes, cellular proteins and DNA

Screening of targeted inhibitors in patient-derived breast tumor cells revealed that PI3K-mTOR inhibitors LY294002 and rapamycin exhibited the strongest selective cytotoxicity compared to matched normal cells (Supplementary Fig