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Mechanistically, the oxidative modification of phospholipids in the plasma membrane promotes structural changes that facilitate GSDMD pore formation, which eventually leads to cell swelling and lysis

Palbociclib and Telaglenastat combination has synergistic antiproliferative effects in vivo To validate our in vitro results, we investigated the effects of the combined administration of Palbociclib and Telaglenastat on the tumor growth of HCT116 cells, xenografted into NOD SCID mice

617, 8493 10.1016/j.abb.2016.08.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 160.Yang G., Zhao K., Ju Y., Mani S., Cao Q., Puukila S.et al

PHILLIPS, REUBEN (1827-1885)