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AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer

Annals of the New York Academy of Sciences , 1033 , 7991

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In summary, SIRT3 enhances FAO by deacetylating and activating CPT2, which subsequently alters the relative content of LC and PC in adipocytes

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