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doi: 10.1016/j.waojou.2021.100614

Dectin-1 Y238x polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient-and donor-dependent mechanisms of antifungal immunity

Glutathione is a tripeptide molecule composed of three amino acids glutamine, cysteine, and glycine that serves as the bodys master antioxidant

Finally, we also confirmed their metabolism linked to glutathione metabolism pathway using in vivo stable-isotope tracing metabolomics in live mice and BSO inhibition in different cell lines (Supplementary Figs

Notably, like proteasome inhibitors, high-dose AUR also transcriptionally induces ChaC1, the rate-limiting enzyme in glutathione (GSH) catabolism [27]
