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Jun 2016;4(6):498-506

After removal of the skin over the right cerebral hemisphere, the skull was cleaned and a 2 2 mm region of skull centered over the primary visual cortex (1.5 mm anterior to lambda0.5 mm posterior to lambda and 1.53.5 mm lateral to bregma) was removed using a high-speed dental drill

Improper injection technique Subcutaneous injection into fatty tissue, not muscle

and G.M.M
There will be quite a lot of water coming out of them