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Acta Neuropsychiatr ., 29 (6), 337346

Furthermore, IGF1 is closely associated with multiple neurological disorders [11]

In preliminary experiments Emp1 was shown to be essential for viability and to influence ER glutathione levels, leading to a more oxidizing ER environment upon overexpression

Since then, 21 individuals are noted in literature who share a characteristic pattern of skeletal anomalies, central nervous system malformations, hypotonia, cardia arrhythmias, and early mortality due to respiratory failure [2,3,4,5,6,7,8,9,10,11,12,13,14]

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