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To further test the hypothesis that the increase in cell death in DADA2 is caused extrinsically by the secretome of ADA2-deficient cells, we collected supernatants of PBMCs from HC and DADA2 patients after 48 h culture in vitro
EC 1.4.3.4), uptake of glutamate and -aminobutyric acid (GABA) by specific transporters and production of antioxidants [2-3,25-27] (Figure 1)
The blood is spun in a centrifuge, which separates the red blood cells from the liquid part of your blood: plasma
The recent progress in developing nanosensors for the visualization of GSH in cells (Bagherpour and PrezGarca 2024

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