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Exercise combined with a low-calorie diet was connected to decreased TMAO levels in obese people, however, bone mineral loss must be considered in interventions

Results from another uncontrolled intervention in 21 HIV-positive patients suggested that long-term (two to four years) oral ALCAR supplementation (1.5 g/day) may be a beneficial adjunct to antiretroviral therapy to improve neuropathic symptoms in some HIV-infected individuals (80, 81)

This reaction is a rate-controlling step for the -oxidation of fatty acid (13)

In patients with CKD, the TMAO levels are often significantly elevated due to impaired renal excretion

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