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Review additional monitoring considerations Example dosing and titration 1/5 standard dosing* Week 1 1 mg/kg/day (0.5 mg/kg twice daily) Week 2 2 mg/kg/day (1 mg/kg twice daily) Week 3 3 mg/kg/day (1.5 mg/kg twice daily) Week 4 4 mg/kg/day (2 mg/kg twice daily) Week 5 5 mg/kg/day (2.5 mg/kg twice daily) * Note: Total dosage should be split and administered twice daily

Decide with a fertility-experienced practitioner.

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Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib (Tao et al., 2016)

Adding this substance in skin care products can speed up the skins absorption and utilization of active ingredients