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A recent study indicates that sickle cell trait with low grade hemolysis is beneficial in malaria infection due to an increased in disease tolerance associated with higher HO-1 expression (23)
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Mechanistic studies propose that it may influence sleep through interactions with GABAergic and opioid systems, but these neurotransmitter interactions remain unconfirmed [10]

The irradiation of compound 1 (50 M) with white light (3.0 mW cm 2 ) resulted in a quantitative conversion of compound 1 ( t R = 10.7 min) into the oxidized compound 2 ( t R = 10.3 min, 97%) over the course of 10 min, as followed by HPLCmass spectrometry (MS) (Fig

Clinical Ophthalmology / PMC (2007) 12
