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Using the Connectivity Map (CMap) [13], we found that the tripeptide Gly-His-Lys (GHK) was able to reverse the aberrant patterns of gene expression associated with increasing emphysema severity and induce patterns of gene expression consistent with transforming growth factor beta (TGF) pathway activation

Liu, B., Zhang, M., Zhao, J., Zheng, M

While levodopa remains the most potent agent for reversing motor deficits in animal models (due to its direct dopaminergic effect), these adjunct natural therapies show significant protective or restorative effects that levodopa alone does not provide (Figure 6)

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