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The introduction of water creates conditions for hydrolysis, microbial growth, and oxidative degradation that are not present during dry storage, so reconstituted material should be handled with more care than the lyophilized powder

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By restoring the physical integrity of the nerve fibers, methylcobalamin helps normalize autonomic nervous system signaling, which is often severely dysregulated in patients dealing with postural orthostatic tachycardia syndrome (POTS) and other forms of post-viral dysautonomia