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927 These results suggest that HDAC3 maintains iron homeostasis through the Hippo/YAP pathway and might represent a target to reduce ferroptosis in iron overload-related diseases
Regarding neuroinflammation, as induced in an animal model of pneumococcal meningitis, it was shown that chronic treatment with CBD (2.5, 5, or 10 mg/kg) significantly reduced TNF- concentrations in the frontal cortex, preventing cognitive impairment [82]

However, upon its delivery to the GI tract, gut microbial GUS enzymes hydrolyse SN-38-G and reactivate it back into its toxic form SN-38, which causes dose limiting diarrhoea 14,15

Kusumoputro S, Au C, Lam KH, Park N, Hyun A, Kusumoputro E, et al

Autor, Ruth Clegg Stanowisko, Reporterka ds