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Initially identified by hyperpigmented patches on hands and feet, these skin changes can serve as visible indicators of B12 deficiency

Without sufficient vitamin B12, the body cannot produce enough healthy red blood cells, leading to a range of symptoms from fatigue to neurological complications

Serum levels of these markers recovered after treatment to normal levels, although less completely in Crohn's disease (114) but also the transcellular uptake of luminal bacteria and bacterial components (123)

Body composition Researched in rodent studies on adipocyte size and lean-versus-fat mass

Michael Adams and Trish (Patricia) Dolan were funded in the UK by Action Medical Research, registration number 208701