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The exception is p.His48Arg in alcohol dehydrogenase 1b 165 and p.Cys282Tyr in homeostatic iron regulator

doi: 10.1152/ajplung.2001.281.6.L1402

Additionally, myoglobin enables a shallow spatial O 2 gradient to exist within the sarcoplasm itself to provide a constant source of O 2 for cellular respiration in muscle cell mitochondria

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This results in a brightening effect and improved skin tone uniformity
