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Bohm F, Kohler UA, Speicher T, Werner S

These patients often find themselves turning to alternative treatments to either complement or follow antibiotic therapy

Beyond neuroendocrine interactions, the bone-brain axis also encompasses com-plex immune crosstalk

Studies in germ-free NOD,MyD88-deficientKO mice also highlight a protective interaction of commensal microbes with the immune system that reduces the incidence of diabetes (110)
However, further cohort studies are required to strengthen these findings
