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Villalobos-Labra, R., Subiabre, M., Toledo, F., Pardo, F
The increased oxidative stress seems to be the second hit in the progression from NAFL to NASH: the increase in ROS and consequently in lipid peroxidation has been associated to hepatocellular damage, inflammation, and eventual fibrosis due to the activation of hepatic stellate cells

GPX1 and 2 are highly expressed in the gastrointestinal epithelium and have been implicated in the development and promotion of colorectal cancer [8]

doi:10.1055/s-0040-1718735 12

Inform patients that their urine might show a reddish/brown discoloration due to the excretion of the iron-deferiprone complex