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Statistical Analysis All data of animal and cell studies were analyzed by SPSS 23.0 (IBM SPSS software, New York, United States), visualized by GraphPad Prism 8.0 (GraphPad Software), and shown as mean SEM

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

doi: 10.3389/fphar.2023.1182788 Received 09 March 2023 Accepted 31 March 2023 Published 06 April 2023 Volume 14 - 2023 Edited by Xuelin Zhou, Capital Medical University, China Reviewed by Yachen Shen, University of Pennsylvania, United States Yusheng Li, University of Mississippi, United States Shengjie Xu, Merck, United States Changlu Xu, University of California, Los Angeles, United States Updates Copyright 2023 Jing, Iba, Naito, Xu, Morishige, Nagata, Okubo and Ando

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When assessing IIEF scores, only two studies [19, 20] identified any benefit (IIEF improvement of between 4.9 and 5.07)