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Lang PA, Beringer O, Nicolay JP, Amon O, Kempe DS, Hermle T, et al

Binding affinity of quercetin and acetazolamide against ACE 2 was expressed in terms of Dissociation Constant (KD) value, which is considered to be inverse of affinity constant (binding affinity 1/KD)

Although the intracerebral injection looked efficient in some studies on animal models, it is also an invasive method

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However, approximately 80% of HGSOC patients initially respond well to platinum-based chemotherapy, so the first-line chemotherapy regimens for HGSOC patients are platinum analogues with the addition of a taxane (paclitaxel or docetaxel)