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In still further embodiments, a formulation or composition disclosed herein is applied at or near the round window membrane via a microinjection device

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Motivated behaviour Behaviour in which actions are energized and directed towards goals, or rewards or towards avoiding aversive conditions

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(151) used recombinant Escherichia coli Nissle 1917 to construct a fusion overexpression system of BMP-2 and CXCR4 with ClyA, a kind of bacterial EV (BEV) surface protein, and finally designed the engineered BEVs-BMP-2-CXCR4

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