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Association of lipoprotein(a) levels with incidence of major adverse limb events

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Considering that myofibroblasts are the primary cell type responsible for ECM accumulation, with TGF- signaling being a key pathway involved [150] and MMPs serving as major endopeptidases responsible for ECM degradation [152], it has been demonstrated that ADSC-EVs effectively mitigate scar formation by modulating ECM remodeling, as anticipated [151]

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