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Background Severe acute malnutrition (SAM) and environmental enteric dysfunction (EED) are highly prevalent among children residing in resource-limited countries like Bangladesh

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Although WT -GCS-GS is nearly uninhibited by GSH (Ki 140 mM), shorter -GCS domain constructs were unexpectedly found to be strongly inhibited (Ki 15 mM), reproducing a physiologically important regulation seen in monofunctional -GCS enzymes