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Description
Image- and fluorescence-based test shows oxidant-dependent damages in red blood cells and enables screening of potential protective molecules
Norris, Jane L
Casadesus, G
In this oxidative milieu, several pathways are agitated, including cystine/glutathione/GPX4, ferroptosis suppressor protein-1/coenzyme Q10 (FSP1/CoQ10) and GTP cyclohydrolase-1/tetrahydrobiopterin/dihydrofolate reductase (GCH1/BH4/DHFR) signalling axis, activating downstream signalling pathways, inducing ferroptosis (Zhao et al
& Carlson, D
