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doi: 10.3389/fmed.2025.1565275 Received 22 January 2025 Accepted 20 May 2025 Published 13 June 2025 Corrected 14 July 2025 Volume 12 - 2025 Edited by Jlio Belo Fernandes, Egas Moniz Center for Interdisciplinary Research (CiiEM), Portugal Reviewed by Ajith Sominanda, Qatar University, Qatar Ricardo Antunes, Egas Moniz Center for Interdisciplinary Research (CiiEM), Portugal Updates Copyright 2025 Anghelescu, Munteanu, Spinu, Ciobanu, Popescu, Cioca, Andone, Stoica, Mandu, Rebedea, Giuvara, Malaelea, Vladulescu-Trandafir, Morcov and Onose

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J Biochem 136(3):261265

Some clinicians consider adding medications from entirely different classes (e.g., naltrexone/bupropion) only after maximizing GLP-1 or GIP agonist therapy alone