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A study conducted post-mortem on the brains of sporadic Parkinson's disease patients showed an accumulation of DOPAL compared to DA in the putamen region of healthy individuals

Protein surface are colored as below: hydrophobic (white), positive charge (red), and negative charge (blue)

Neuropeptide hormones and receptors common to the immune and neuroendocrine systems: bidirectional pathway of intersystem communication

N., et al., Limiting Endosomal Damage Sensing Reduces Inflammation Triggered by Lipid Nanoparticle Endosomal Escape, Nature Nanotechnology 20 (2025): 12851297
Gleeson M, Pyne DB