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[DOI] [PMC free article] [PubMed] [Google Scholar] 144.Klomsiri C, Nelson KJ, Bechtold E, Soito L, Johnson LC, Lowther WT, Ryu S-E, King SB, Furdui CM, Poole LB

According to Rossignol and Frye, indirect biochemical markers of mitochondrial dysfunction appear to be abnormal in the general ASD population, occurring at a much higher frequency than direct biomarkers [38]

Pharmacokinetic work indicates an extended half-life of roughly 159195 hours, supporting once-weekly administration and steady receptor engagement

Ageing Res Rev 2023;92:102066
The physicochemical characteristics of the surrounding environment (thermal injury, pH, osmolality, oxidative stress, and plasma protein profile) also play a major role
