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Flavone biosynthesis is initiated by chalcone synthase, followed by chalcone isomerase 12 , which produces flavanones as precursors for the later synthesis of both flavones and other major flavonoid classes

Summed intensities were log 2 -transformed

these are regulated as foods under Food Standards Agency (FSA) rules rather than as medicines, and are therefore not subject to the same rigorous clinical evaluation as licensed medicinal products

[DOI] [PubMed] [Google Scholar] 26.Lowry E., Marley J., McVeigh J.G., McSorley E., Allsopp P., Kerr D

Nonteratogenic Effects: Because of the known effects of nonsteroidal anti-inflammatory drugs on the fetal cardiovascular system (closure of ductus arteriosus), use during pregnancy (particularly late pregnancy) should be avoided