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A large body of research has demonstrated a wealth of such protective effects, most notably cardiometabolic, neurological, musculoskeletal, and immunological in nature [2]
IR and T2DM, as core components of endocrine dysfunction, play a central role in the development and progression of MASLD, representing a broad area for ongoing research into novel therapeutic approaches [61]

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Consistently, -syn species have been shown to impair complex I activity and increase reactive oxygen species (ROS) production in cellular and stem-cell models [29, 193, 201]