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Freezing must be strictly avoided, as freezing can cause irreversible damage to the peptide structure of tirzepatide and may alter the formulation characteristics
Ben David A, Papir Y, Hazan O, Redelman M, Diamant E, Barnea A, et al

Hurst, R., Bao, Y., Jemth, P., Mannervik, B

10.1021/acs.biochem.7b01305
