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GH secretion [2]: Is low during childhood but increases slightly until puberty Is greatly increased during puberty until it decreases in late adolescence Remains stable until approximately 30 years old in age Progressively declines from 30 years old on Role of Growth Hormone in Growth GH acts both directly and by stimulating IGF-1 [2]
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van der Lely AJ, Tschp M, Heiman ML, Ghigo E
