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These metabolites are generated by bacteria such as Clostridium and Desulfovibrio , which are frequently enriched in PD [25]

On the other hand, another study found no effect of 2000 mg NR per day supplementation in obese or overweight men on NAD + metabolite or mitochondria in skeletal muscle, although muscle NAMPT levels were decreased 316

Thus, it is important to elucidate the toxic mechanism of gliotoxins

Using the extinction coefficient (155 mM -1 cm -1 ) the TBARS content was calculated