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The overlap of docked conformations for 7-HMG and corynoxine A suggests C15 and C20 are critical anchors for productive hMOR binding, consistent with earlier reports that mitragynine-derived ligands exploit these regions to stabilize distinct active states (Varadi et al., 2016

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An example of a material that shows resistance to dissolving even when subjected to high temperatures and pressures is SiO 2 polymers (200, 209)

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