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In a report by Olivia Clinic , serious side effects such as kidney failure or blood poisoning can occur when the dosage is much higher than what is required
J Bioenerg Biomembr (2001) 33(6):493501
10.1172/JCI94495 23 ChiouJ.GeuszR
A Comprehensive Review of Microfluidic Approaches in Cell-Free Synthetic Biology
If another matrix was used with a much higher exclusion limit the separation would be more effective.
