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Thus, experiments with ovariectomized (OVX) rats have shown a reduction in the anti-oxidant activity of superoxide dismutase (SOD) in the hippocampus, a process that contrasts with an increase in the pro-oxidant enzyme monoamine oxidase (MAO) in the same region (Huang and Zhang, 2010)

Polymorphisms of these genes or associated regulatory sequences, or copy number variations (CNV) may contribute to a reduction in UGT activity or indeed loss of function and, therefore, reduce paracetamol glucuronidation

An investigation revealed that specific tumor-infiltrating immune cells (primarily resting mast cells) displayed a negative correlation with a FRG signature, which has the capacity to precisely predict the prognosis of UM (65)

doi: 10.1016/j.biochi.2012.11.004

10.1016/j.tplants.2014.02.001 Trends Plant Sci