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First, under normal conditions, elevated HO1 expression attenuates oxidative stress to exert cytoprotective effects, and second, sustained HO1 upregulation releases ferrous iron to exacerbate oxidative stress, which leads to ROS accumulation through the Fenton reaction

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Appearance: White crystalline powder Odor and taste: Almost odorless, sour taste Arsenic (As): 2 ppm Assay: 98.0 % Heavy Metals: 10 ppm Identification (IR): Corresponds Identification (Lead Acetate): Positive Identification (Ninhydrin): Positive Iron (Fe): 10 ppm Loss on Drying: 0.5 % Melting Point: About 185 o C Optical Rotation: -21 - -11 o Residue on Ignition: 0.1 % Solubility: Soluble in water Solution: Clear solution BSE/TSE Free: BSE/TSE Free Country of Origin: Report G22010 Revision#2 SDS_21.pdf Download Certificate of Analysis Product Recommendations List Price $ 41 .45 Price $ 39 .95 You Save $ 1 .50 List Price $ 41 .45 Price $ 39 .95 You Save $ 1 .50 List Price $ 41 .45 Price $ 39 .95 You Save $ 1 .50 List Price $ 41 .45 Price $ 39 .95 You Save $ 1 .50 List Price $ 41 .45 Price $ 39 .95 You Save $ 1 .50 List Price $ 237 .50 Price $ 225 .75 You Save $ 11 .75 List Price $ 237 .50 Price $ 225 .75 You Save $ 11 .75 List Price $ 1427 .55 Price $ 1360 .00 You Save $ 67 .55 List Price $ 68 .40 Price $ 66 .99 You Save $ 1 .41 List Price $ 75 .50 Price $ 70 .99 You Save $ 4 .51

Our recent studies have shown that PDI plays an important role in mediating chemically-induced, GSH depletion-associated oxidative cytotoxicity in a number of cell lines [22,23,24]