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Hydroxocobalamin tends to remain in the body longer and is more readily converted to the active coenzyme forms of B, which can make it effective for maintaining B levels

Indeed, in experimental animal models, the overexpression of CTGF alone leads only to mild fibrosis [98,99,100,101,102]
Further, we provide an overview on the limitations of the current research on the topic and insights for future studies to establish standardized AOX regimens and to assess their long-term impact on key outcomes such as live birth rates and miscarriage rates

In high doses, the most serious adverse effect is a dose-dependent, potentially fatal hepatic necrosis