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Neurobiol Dis 29: 456464, 2008

DSVs actively generate hydrogen sulfide (H2S) through sulfate reduction by utilizing sulfate as an electron acceptor during the respiration and increase H2S production, which causes severe damage to the CNS (78)

The liver, in particular, relies heavily on glutathione for detoxification processes

Because AOD9604 interacts with energy-regulation and lipid-related pathways, metabolite profiling can reveal shifts in substrate utilization, organic acid patterns, amino acid turnover, and lipid intermediates

Patients also appreciate that B12 injections are simple, fast, and easy to incorporate into an existing routine