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Given the importance of myelin to CNS health, a wide body of MS research focuses on understanding the vulnerability of oligodendrocytes and their associated myelin sheaths to identify novel strategies to improve myelin regeneration, otherwise known as remyelination, and to slow neurodegeneration

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Acknowledgements This work was supported by the Novo Nordisk Foundation, CEMBID (Center for Multifunctional Biomolecular Drug Design), Grant Number: NNF17OC0028070, and the Spanish Ministry of Economy and Competitiveness (SAF2017-89437-P)