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Furthermore, the increased levels of tau phosphorylation were significantly reduced by the inhibition of GSK-3, CDK5, and calpain, indicating that tau kinases activated by calcium overload are directly involved in the increase of tau phosphorylation
It also examines the proteins they use to signal other cells in the immune system and the nearby neurons
The expression of the remaining 18 genes, including ORC4 , BCL11B , and PAG1 , which were upregulated in the patients not treated with L-serine, was reduced following L-serine treatment
Am J Kidney Dis 32:853906
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