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Histological analysis using Sirius Red and Massons Trichrome staining revealed extensive fibrosis in WT kidneys post-UUO, which was significantly attenuated in Usp2 KO mice (Fig

Optimal functioning of these systems is crucial to reducing your risk of chronic, age-related diseases like diabetes, coronary heart disease, osteoporosis and inflammatory disorders

Unlike autophagy or apoptosis, ferroptosis is specifically triggered by dysregulated lipid metabolism and impaired antioxidant defense, not by activation of established pathways like caspase

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