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Temporary breaks or dosage reduction can minimize unwanted effects while maintaining benefits

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it is likely to translate into better real-world adherence, and better adherence is the most important determinant of long-term therapeutic outcomes in chronic disease management

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G proteins mediate a wide variety of cellular functions, including, but not limited to, altering the production of second messengers such as cyclic adenosine monophosphate (cAMP), mobilizing internal calcium stores, modulating ion channel function, altering neurotransmitter release, and influencing gene expression