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Description
Romidepsin is used for treatment of cutaneous T-cell lymphoma (CTCL) and other peripheral T-cell lymphomas (PTCLs)

However, in response to pathological or exogenous stimuli, antioxidant pathways are overloaded with excessive ROS, leading to oxidative stress, which causes damage to lipids, proteins, and DNA (Sies, 2015

Redox-cycling and intercalating properties of novel mixed copper(II) complexes with non-steroidal anti-inflammatory drugs tolfenamic, mefenamic and flufenamic acids and phenanthroline functionality: structure, SOD-mimetic activity, interaction with albumin, DNA damage study and anticancer activity

doi: 10.1002/j.2040-4603.2016.tb00690.x 13

High levels of plasma MPO-DNA complex and aberrant NET formation are correlated with severe ARDS in COVID-19 (Middleton et al., 2020
