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363,364 This inhibition is believed to occur through the suppression of LPS-induced TNF- production in macrophages

A 6MWT was repeated at 9 months after dosing (two ARA 290 patients and one placebo patient were lost to follow-up)

Whereas triacylglycerol (TAG)-DHA had minimal effect on brain DHA, di-DHA PC (phosphatidylcholine) and LPC-DHA markedly and dose dependently increased the DHA in all regions of the brain 25