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S.ZhangZ.ZhangF.SinghS.et al (2017)
Left panel : Low-dose IV ACh primarily activates endothelial M3 muscarinic receptors, stimulating nitric oxide (NO) release and vascular smooth muscle relaxation, resulting in arterial vasodilation and reduced blood pressure

Patients report smoother, more even-toned skin with improved elasticity

People may struggle with focus, memory, or mental clarity

Rasool et al., 2022)