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Long-term use may lead to reduced efficacy and increased adverse effects (Xu et al., 2023)

Curr Drug Targets 2006, 7: 1505-1512

Blocked blood vessels not in the heart or brain

Honestly, though, it's a critical, non-negotiable element researchers need to fully grasp, especially as oral delivery becomes an increasingly viable route for these potent molecules

This results in a net dipole moment, which makes glutamine a polar molecule
