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That is exactly the lens through which I read this research: cautiously, individually, and never as a one-size-fits-all promise

Nintedanib had a manageable AE profile, but a limited activity in relapsed or refractory SCLC

A 2021 analysis of three-year follow-up data from the EDICT (Efficacy and Durability of Initial Combination Therapy) randomized controlled trial found that initiation of triple therapy with metformin, pioglitazone, and exenatide at the time of diagnosis not only led to greater improvements in HbA1C values at six months, it also significantly reduced HbA1C levels by 0.5% more than sequential initiation of metformin followed by glipizide and insulin in diabetics with a HbA1C value of approximately 9% (Abdul-Ghani 2021)

Some water retention is common, particularly in the first few weeks

Honesty is crucial here