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Too much bleeding can result in severe anemia, which can also be fatal

If a patient finds themselves needing it more often than 2 doses per week, a re-evaluation of underlying issues or alternative therapies may be warranted

Shao L, Li Q-H, Tan Z

However, the results are typically modest and require large doses

Shrager, S., Voin, V., Iwanaga, J., Tubbs, R
