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These findings indicated that co-ultraPEALut effectively alleviates A-induced neuroinflammation and neuronal injury (56)

So the similarity in the constraints of 1-Cys and 2-Cys reduction facilitates this second Cys acquisition step, but an additional constraint is that the second Cys must be the resolving Cys and thus have a higher pKa than the existing Cys

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10.1016/j.jaut.2020.102465 J

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