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HCT-116 cells were treated with 50 M 5-FU for 48 h, 2 h after applying 1 M IKE, 100 nM CB-839, and 100 M Polydatin

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Oxidative stress is tied not only to poor sleep but also to chronic conditions such as heart disease, neurological problems, and inflammation

The fractions were dissolved in deuterated methanol to achieve 30 mg/mL and put in NMR tubes (Cortec Net, Les Ulis, France)